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INS — MAFB

Text-mined interactions from Literome

Nishimura et al., Dev Biol 2008 : We show that MafB can directly activate expression of insulin and glucagon, and a MafB protein engineered to contain N248S mutation in the MafB ( kr ( ENU ) ) results in significantly reduced activation
Artner et al., J Endocrinol 2008 : However, only MafA over-expression selectively induced endogenous Insulin mRNA production in cell line based assays, while MafB specifically promoted Glucagon expression ... Ectopic expression of MafA, but not MafB , promoted Insulin production ; however, neither MafA nor MafB were capable of inducing Glucagon