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JUN — MAP2K6
Text-mined interactions from Literome
Manna et al., Oncogene 1999
:
gamma-GCS also abolished the activation of
AP-1 induced by TNF and
inhibited TNF induced activation of JNK and
mitogen activated protein kinase kinase
Naumann et al., J Biol Chem 1999
:
The
c-Jun activation caused by Sgn2 overexpression is
independent of JNK and
mitogen activated protein kinase kinase 4
Manna et al., J Immunol 2000
:
Vesnarinone also blocked NF-kappa B activation induced by several other inflammatory agents,
inhibited the TNF induced activation of transcription factor
AP-1 , and suppressed the TNF induced activation of c-Jun N-terminal kinase and
mitogen activated protein kinase kinase
Andreone et al., J Immunol 2003
:
In murine wild-type fibroblasts, oxidative challenge by peroxynitrite and hydrogen peroxide or immunological challenge by IL-1 and 20 % FCS induced phosphorylation of the
mitogen activated protein kinase kinase-4 ,
activation of
c-Jun N-terminal kinase (JNK) , and DNA binding of AP-1
Ryborg et al., Acta Derm Venereol 2004
:
The effects on transglutaminase-1 and
AP-1 were
dependent on protein kinase C and
mitogen activated protein kinase kinase
Lotan et al., Cancer Res 2008
(Neoplasm Metastasis...) :
c-Jun NH2-terminal kinase activating kinase
1/mitogen activated protein kinase kinase 4-mediated
inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation