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MMP1 — RAC3
Text-mined interactions from Literome
Westermarck et al., Mol Cell Biol 2001
(MAP Kinase Signaling System) :
In contrast, activation of stress activated c-Jun N-terminal kinase and p38 pathways by expression of constitutively active mutants of
Rac , transforming growth factor beta activated kinase 1 ( TAK1 ), MAPK kinase 3 ( MKK3 ), or MKK6 or by treatment with arsenite or anisomycin did not alone markedly
enhance MMP-1 promoter activity
Newberry et al., Mol Endocrinol 1997
:
Dominant negative Ras abrogates
MMP1 induction by constitutively active FGFR2-ROS, but dominant negative Rho and
Rac do not
inhibit induction