Gene interactions and pathways from curated databases and text-mining

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MAPK14 — MSK9

Text-mined interactions from Literome

Ryder et al., J Biol Chem 2000 : Stimulation of MSK1 in contracting skeletal muscle required the activation of both ERK and p38 ( MAPK )
Markou et al., Biochem J 2002 : Phosphorylation and activation of MSK1 was completely inhibited by either PD98059 ( ERK1/2 pathway inhibitor ) or SB203580 ( p38 MAPK inhibitor ) alone
Brami-Cherrier et al., J Neurochem 2007 : Blocking activation of mitogen- and stress activated kinase 1 ( MSK1 ), a kinase downstream ERK and p38 MAPK , by pharmacological approach or using striatal cells from MSK1 deficient mice, totally abolished H3 phosphorylation, as well as c-Fos and c-Jun induction
Nagy et al., J Mol Cell Cardiol 2007 (MAP Kinase Signaling System) : Since CREB is a downstream target of MSK-1 ( mitogen- and stress activated protein kinase-1 ) situated at the crossroad of ERK ( extracellular receptor kinase ) and p38MAPK signaling pathways, we reasoned that MSK-1 could be a downstream molecular target for p38MAPK and ERK signaling in the IPC hearts
Deak et al., EMBO J 1998 : Mitogen- and stress activated protein kinase-1 ( MSK1 ) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB