Gene interactions and pathways from curated databases and text-mining

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MAPK4 — MUC1

Text-mined interactions from Literome

Ríos et al., Exp Eye Res 2008 (MAP Kinase Signaling System) : The purpose of the study was to determine if OPC-12759 stimulates secretion from conjunctival goblet cells in culture and if it activates the EGF receptor (EGFR) and p44/p42 mitogen activated protein kinase ( MAPK ) to cause mucin secretion
Román et al., Eukaryotic cell 2009 (Candidiasis) : Msb2 signaling mucin controls activation of Cek1 mitogen activated protein kinase in Candida albicans
Besmer et al., Cancer Res 2011 (Carcinoma, Pancreatic Ductal...) : Treatment with a MEK1/2 inhibitor, U0126, abrogated the enhanced proliferation of the KCM cells but had minimal effect on KCKO cells, suggesting that MUC1 is necessary for MAPK activity and oncogenic signaling
Kato et al., J Immunol 2012 (Lung Diseases...) : However, overexpression of MUC1 in HEK293 cells did not affect NF-?B or MAPK activation in response to TNF-a