Gene interactions and pathways from curated databases and text-mining

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AKT2 — PDGFA

Text-mined interactions from Literome

Chen et al., Am J Physiol Cell Physiol 2002 : Ad-PDGF-A induces sustained phosphorylation of PDGFalphaR as well as prolonged phosphorylation of downstream extracellular signal regulated kinase 1/2 and Akt signaling pathways
Zheng et al., J Neurosci Res 2010 : In particular, PDGF-AA induced activation of Akt was at very low level
Wang et al., Invest Ophthalmol Vis Sci 2010 : Rat lens epithelial explants were used to compare the ability of vitreous, IGF-1, PDGF-A , EGF, and FGF-2 to stimulate the phosphorylation of ERK1/2 and Akt leading to fiber differentiation, in the presence or absence of selective receptor tyrosine kinase ( RTK ) inhibitors
McGowan et al., Pediatr Res 2011 : Using cultures of neonatal mouse LF, we showed that imatinib did not suppress PDGF-Ra gene expression but reduced PDGF-A mediated Akt phosphorylation, potentially explaining the increase in apoptosis
Feng et al., Oncogene 2012 (Disease Progression...) : Inhibition of Src by Src inhibitors attenuated PDGF-A stimulated phosphorylation of Akt and Dyn2 and glioma cell migration