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AKT2 — PDGFA
Text-mined interactions from Literome
Chen et al., Am J Physiol Cell Physiol 2002
:
Ad-PDGF-A induces sustained phosphorylation of PDGFalphaR as well as prolonged phosphorylation of downstream extracellular signal regulated kinase 1/2 and
Akt signaling pathways
Zheng et al., J Neurosci Res 2010
:
In particular,
PDGF-AA induced activation of
Akt was at very low level
Wang et al., Invest Ophthalmol Vis Sci 2010
:
Rat lens epithelial explants were used to compare the ability of vitreous, IGF-1,
PDGF-A , EGF, and FGF-2 to
stimulate the phosphorylation of ERK1/2 and
Akt leading to fiber differentiation, in the presence or absence of selective receptor tyrosine kinase ( RTK ) inhibitors
McGowan et al., Pediatr Res 2011
:
Using cultures of neonatal mouse LF, we showed that imatinib did not suppress PDGF-Ra gene expression but reduced
PDGF-A mediated
Akt phosphorylation, potentially explaining the increase in apoptosis
Feng et al., Oncogene 2012
(Disease Progression...) :
Inhibition of Src by Src inhibitors attenuated
PDGF-A stimulated phosphorylation of
Akt and Dyn2 and glioma cell migration