Gene interactions and pathways from curated databases and text-mining

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IL8 — PLD3

Text-mined interactions from Literome

Atta-ur-Rahman et al., Curr Pharm Des 1999 (Inflammation) : Neutrophils activation of phospholipase D ( PLD ) and superoxide generation in response to IL-8 have also been demonstrated
Conquer et al., Osteoarthritis Cartilage 1994 : Effect of interleukin 1, lipopolysaccharide and phorbol esters on phospholipase D activity in chondrocytes
Grab et al., Biochim Biophys Acta 2004 : Differential role for phospholipase D1 and phospholipase D2 in 12-O-tetradecanoyl-13-phorbol acetate stimulated MAPK activation, Cox-2 and IL-8 expression
Bacon et al., J Immunol 1995 : By contrast, this IL-8 dependent PLD activity was undetectable in IL-8 stimulated neutrophils
L'Heureux et al., Blood 1995 : Diverging signal transduction pathways activated by interleukin-8 and related chemokines in human neutrophils : interleukin-8 , but not NAP-2 or GRO alpha, stimulates phospholipase D activity ... The ability of IL-8 to stimulate the activity of PLD was additively enhanced, or primed, by cytochalasin B and by tumor necrosis factor alpha
Sozzani et al., Blood 1994 : Activation of phospholipase D by interleukin-8 in human neutrophils