Gene interactions and pathways from curated databases and text-mining

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CD79B — PLD4

Text-mined interactions from Literome

Hitomi et al., FEBS Lett 1999 : Herein we provide biochemical and genetic evidence that cross linking of the B cell receptor (BCR) induces rapid activation of PLD through a Syk-, Btk- and phospholipase C (PLC)-gamma2 dependent pathway in DT40 cells ... These results demonstrate that Syk, Btk and PLC-gamma2 are essential for BCR induced PLD activation
Snyder et al., Traffic 2006 : Thus, the investigation of the mechanism by which Y112-LMP2A blocks BCR function revealed an essential role for PLD in BCR trafficking for antigen processing