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EPHB2 — PML

Text-mined interactions from Literome

Son et al., Cancer Lett 2007 (Breast Neoplasms) : We concluded that PML and all-trans-retinoic acid cause cell death by different pathways : PML activates ERK1/2 , p38 MAPK, and p21 ; arrests the cell cycle ; and later causes cell death ; and all-trans-retinoic acid activates proteasome function, caspase cleavage, and apoptosis
Barbarroja et al., Br J Haematol 2008 (Cell Transformation, Neoplastic...) : To our knowledge, this is the first report to show that PML/RARalpha was suppressed by MEK/ERK inhibition, through a mechanism dependent on caspase activation
Lim et al., J Biol Chem 2011 : Taken together, our results support a model in which Pin1 promotes PML degradation in an ERK2 dependent manner