Gene interactions and pathways from curated databases and text-mining

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POU5F1 — TP53

Text-mined interactions from Literome

Campayo et al., Eur Respir J 2013 : miR-145 regulates SOX2 and OCT4 translation and p53 regulates miR-145 expression
Jackson et al., Cell cycle (Georgetown, Tex.) 2013 (Ovarian Neoplasms) : Reduction of TP53 using sh- or si-RNA prevented the upregulation of OCT4A and P21CIP1 and increased DNA damage
Gutekunst et al., Cancer Res 2013 (Neoplasms, Germ Cell and Embryonal...) : We previously showed that p53 is a major player in cisplatin hypersensitivity and therefore investigated whether Oct-4 may directly affect p53 activity
Ren et al., Int J Oncol 2013 (Prostatic Neoplasms) : Moreover, WT-p53 also suppressed colony formation, tumor sphere formation and expression of CSC markers and stemness factors including CD44, Oct4 , c-Myc and Klf4 in PC-3 cells