Gene interactions and pathways from curated databases and text-mining

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NOS2 — PRG4

Text-mined interactions from Literome

van den Berg et al., Osteoarthritis Cartilage 1999 (Arthritis...) : NOS2 deficiency prevented chondrocyte proteoglycan synthesis inhibition in the arthritic cartilage and restored normal responsiveness to IGF-1
Shin et al., J Appl Physiol 2003 : Stimulation of proteoglycan release in response to compression was dependent on NOS2 regardless of the presence of IL-1
Fermor et al., Osteoarthritis Cartilage 2004 : TNF-alpha prevented the mechanical stimulation of proteoglycan synthesis, and this effect was not dependent on NOS2