Gene interactions and pathways from curated databases and text-mining

◀ Back to ABL1

ABL1 — PRKD1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: PRKD1 → ABL1 (directlyIncreases, PRKD1 Activity)
    Evidence: 12637538;12505989
  • OpenBEL Selventa BEL large corpus: PRKD1 → ABL1 (directlyIncreases, PRKD1 Activity) Storz et al., Mol Cell Biol 2004*
    Evidence: Protein kinase D (PKD) participates in activation of the transcription factor NF-kappaB (nuclear factor kappaB) in cells exposed to oxidative stress, leading to increased cellular survival. We previously demonstrated that phosphorylation of PKD at Tyr463 in the PH (pleckstrin homology) domain is mediated by the Src-Abl pathway and that it is necessary for PKD activation and subsequent NF-kappaB induction.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *