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PRL — TP53
Text-mined interactions from Literome
Levina et al., Cancer Res 2009
(Genital Neoplasms, Female) :
Binding of
PRL to its receptor was
followed by rapid phosphorylation of extracellular signal regulated kinase ( ERK ) 1/2, mitogen activated protein kinase/ERK kinase 1, signal transducer and activator of transcription 3, CREB, ATF-2, and
p53 and activation of 37 transcription factors in ovarian and endometrial carcinoma cells
Fritsche et al., Mol Cell Endocrinol 1998
:
p53 repressed the
prolactin induction of the Stat5 mediated transcription of the beta-casein promoter-luciferase reporter gene, but did not affect IFN-gamma induced, Stat1 dependent transcription of the IRF-1 promoter