Gene interactions and pathways from curated databases and text-mining

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IL8 — PRTN3

Text-mined interactions from Literome

Hsieh et al., Clin Rheumatol 2007 : The spontaneous membrane expression of MPO and PR3 on PMN could be significantly increased by lipopolysaccharide (LPS) and TNF-alpha, but not by IL-8 or GRO-alpha
Csernok et al., Clin Exp Immunol 1994 (Wegener Granulomatosis) : In addition, TNF-alpha and both forms of IL-8 act synergistically and induce a translocation of PR3 from the intragranular loci to the cell surface of PMN
Mayet et al., Blood 1993 (Wegener Granulomatosis) : We were able to show that tumor necrosis factor-alpha, interleukin-1 alpha/beta, and interferon-gamma led to an increased PR-3 expression in the cytoplasm of endothelial cells by performing polymerase chain reaction analysis, Western blot, cyto-enzyme linked immunosorbent assays, and confocal laser scanning microscopy
Berger et al., J Am Soc Nephrol 1996 (Autoimmune Diseases...) : The presence of both proteinase 3 and elastase resulted in an increased production of IL-8 , up to 15.6- and 4.2-fold, respectively, in a dose- and time dependent fashion