Gene interactions and pathways from curated databases and text-mining

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IGF1 — PSMG1

Text-mined interactions from Literome

Jamen et al., J Neurochem 2002 (MAP Kinase Signaling System) : In cerebellar granule cells, IGF-1 and brain derived neurotrophic factor (BDNF) also stimulated the activity of the PAC1 promoter ... In cerebellar granule cells, IGF-1 and brain derived neurotrophic factor (BDNF) also stimulated the activity of the PAC1 promoter ... NGF and IGF-1 increased endogenous PAC1 mRNA levels, and the NGF induced up-regulation is the result of an increase in transcription from PAC1 promoter instead of an increase in mRNA stability
Delcourt et al., EMBO J 2007 : PAC1R transactivation was responsible for a large fraction of the IGF-1 associated phosphoproteome and played a critical role in the antiapoptotic activity of IGF-1