We have a suspicion that you are an automated web bot software, not a real user. To keep our site fast for other users, we have slowed down this page. The slowdown will gradually disappear. If you think this is a mistake, please contact us at genome-www@soe.ucsc.edu. Also note that all data for hgGeneGraph can be obtained through our public MySQL server and all our software source code is available and can be installed locally onto your own computer. If you are unsure how to use these resources, do not hesitate to contact us.
UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to MTOR


Text-mined interactions from Literome

Narita et al., Science 2011 : mTOR recruitment to the TASCC was amino acid- and Rag guanosine triphosphatase dependent , and disruption of mTOR localization to the TASCC suppressed interleukin-6/8 synthesis
DurĂ¡n et al., Mol Cell 2012 : Constitutively active Rag heterodimer activated mTORC1 in the absence of glutaminolysis
Narita et al., Small GTPases 2012 : Thus, the TASCC provides evidence for the functional relevance of the Rag mediated association between lysosomes and mTOR , and provides a mechanism for the simultaneous activation of anabolic and catabolic processes
Sancak et al., Science 2008 : Conversely, expression of a guanosine diphosphate bound Rag mutant prevented stimulation of mTORC1 by amino acids
Settembre et al., EMBO J 2012 : Interestingly, the Rag GTPase complex, which senses lysosomal amino acids and activates mTORC1 , is both necessary and sufficient to regulate starvation- and stress induced nuclear translocation of TFEB
Sancak et al., Cell 2010 (MAP Kinase Signaling System) : Thus, Rag-Ragulator mediated translocation of mTORC1 to lysosomal membranes is the key event in amino acid signaling to mTORC1