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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

◀ Back to EGFR

EGFR — SEC14L2

Text-mined interactions from Literome

Nishi et al., J Biol Chem 2001 : However, our results indicate that TAp63gamma has a very low ability to bind to the EGFRp53RE and surprisingly represses both basal EGFR promoter activity and endogenous EGFR expression ... Transient transfection assays show that the EGFR promoter region between -348 and -293, containing two Sp1 sites, is crucial for the repression of the EGFR expression by TAp63gamma ... These results suggest that TAp63gamma is involved in the regulation of the EGFR gene expression through interactions with basal transcription factors
Klanrit et al., Oncogene 2009 (Head and Neck Neoplasms) : Expression of TAp73beta efficiently induced promyelocytic leukaemia (PML) protein expression and PML knockdown by shRNA attenuated the downregulation of EGFR and induction of apoptosis by p73 in HNSCC cells