Gene interactions and pathways from curated databases and text-mining

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PRKAB1 — SLC2A1

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Winder et al., J Appl Physiol 2000 : This study was designed to determine whether chronic chemical activation of AMPK will increase mitochondrial enzymes, GLUT-4 , and hexokinase in different types of skeletal muscle of resting rats
Fryer et al., Biochem J 2002 : Long-term ( 5 days ) expression of the constitutively active AMPK mutant increased protein expression of GLUT1 , GLUT4 and hexokinase II, consistent with previous reports on the chronic treatment of rats with AICA riboside
Barnes et al., J Cell Sci 2002 : Activation of GLUT1 by metabolic and osmotic stress : potential involvement of AMP activated protein kinase (AMPK)
Li et al., Brain Res 2006 : Compared with control cells, GLUT2 overexpression resulted in significantly increased cellular ATP levels at 5 and 25 mM glucose concentrations, more inhibition of agouti related peptide (AgRP) mRNA and AMP activated protein kinase (AMPK) phosphorylation by glucose, and attenuated stimulation of AgRP mRNA and AMPK by 2-deoxy-d-glucose ( 2DG ), implicating that brain GLUT2 may be important in the regulation of food intake