Gene interactions and pathways from curated databases and text-mining

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ANGPT2 — SLC9A3

Text-mined interactions from Literome

du Cheyron et al., Kidney Int 2003 : Ang II ( 10-10 mol/L, 43 minutes ) increased NHE3 activity and biotinylated NHE3 protein without any change in total amount of NHE3 protein
He et al., J Biol Chem 2010 : In conclusion, our current findings demonstrate that IRBIT is critically involved in mediating activation of NHE3 by ANG II via a Ca ( 2+ ) /calmodulin dependent protein kinases II-dependent pathway
Banday et al., American journal of physiology. Renal physiology 2011 : Oxidative stress has been shown to upregulate AT1R function that could modulate the ANG II-mediated NHE3 regulation ... We conclude that ANG II stimulates NHE3 via AT1R-PLC-CaM pathway and inhibits NHE3 by AT1R-PKG activation