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EGF — SLC9A3

Text-mined interactions from Literome

Donowitz et al., Ann N Y Acad Sci 2000 : Short-term regulation of NHE3 by EGF and protein kinase C but not protein kinase A involves vesicle trafficking in epithelial cells and fibroblasts
Li et al., J Physiol 2001 : 2. The raft pool of NHE3 was involved in the stimulation of BB NHE3 activity with epidermal growth factor (EGF)
Li et al., Gastroenterology 2004 : In Caco-2 cells, while EGF stimulated BB NHE3 , Akt2 was active in both LR and DS pools
Drumm et al., Cell Physiol Biochem 2006 : The aim of this study was to investigate whether aldosterone acts directly on proximal tubule cells to stimulate NHE3 and if so whether the EGF-receptor (EGFR) is involved ... The underlying mechanisms include AG1478 inhibitable kinase and are paralleled by enhanced EGFR expression, which could be compatible with EGF-receptor-pathway dependent surface expression and activity of NHE3 in human primary renal proximal tubule epithelial cells
Sarker et al., Am J Physiol Cell Physiol 2011 : The stimulatory effect of EGF on NHE3 was eliminated in NHERF1-KD but occurred normally in NHERF2-KD cells ... Stimulation of NHE3 activity by EGF is NHERF1 dependent