Gene interactions and pathways from curated databases and text-mining

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CASP9 — STX2

Text-mined interactions from Literome

Kojio et al., FEMS Immunol Med Microbiol 2000 : The findings suggest that Stx1 as well as Stx2 activate caspase-3 , which plays a critical role in apoptosis, and that the apoptotic signals rise after Stx is transported to the Golgi apparatus
Nakamura et al., Biochem Pharmacol 2003 : However, inhibition of Stx2 mediated caspase activity by terbutaline was partially blocked by cAMP-PKA inhibitors ... On the other hand, p38MAPK inhibition by terbutaline prevented Stx2 induced apoptosis and caspase activity through a cAMP independent pathway via beta(2)-adrenoceptor