Gene interactions and pathways from curated databases and text-mining

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EPHB2 — SYN3

Text-mined interactions from Literome

Gao et al., Arthritis Res Ther 2006 (Arthritis, Experimental) : Cultivation of mouse synovial fibroblasts with IL-1beta activates mitogen activated protein kinases, including extra-cellular signal regulated kinase ( Erk ), JNK ( c-Jun N-terminal kinase ), and p38, while only Erk-specific inhibitor blocks IL-1beta induced SYN expression ... Inhibition of Erk activation reduces ETS1 phosphorylation and SYN expression
Giachello et al., J Cell Sci 2010 : However, the physiological role of MAPK/Erk dependent synapsin phosphorylation in regulating synaptic formation and function is poorly understood ... Our findings show that MAPK/Erk dependent synapsin phosphorylation has a dual role both in the establishment of functional synaptic connections and their short-term plasticity, indicating that some of the multiple extranuclear functions of MAPK/Erk in neurons can be mediated by the same multifunctional presynaptic target