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MAPK7 — TAT
Text-mined interactions from Literome
Mischiati et al., AIDS 1999
(MAP Kinase Signaling System) :
Moreover, both
GST-Tat2E and GST-Tat1E also
stimulated ERK/MAPK
Bruce-Keller et al., J Neurochem 2001
:
Lastly, pre-treatment of microglial cells with physiological concentrations of 17 beta-estradiol suppressed Tat mediated microglial activation by interfering with
Tat induced
MAPK activation
Sui et al., J Immunol 2006
:
Thus, the inhibition of p38 MAPK and JNK protected neurons from Tat induced apoptosis, whereas the inhibition of p38
MAPK , but not of JNK, was
sufficient to prevent
Tat- and gp120 mediated activation of monocytes
Gee et al., J Immunol 2007
:
IL-10 regulation by
HIV-Tat in primary human monocytic cells : involvement of calmodulin/calmodulin dependent protein kinase
activated p38
MAPK and Sp-1 and CREB-1 transcription factors
Bai et al., BMC infectious diseases 2008
:
The effects of HIV-1
Tat on barrier function of the RPE may be
mediated by ERK
MAPK and NF-kappaB activation, which may represent potential targets for novel therapeutic approaches for the retinopathy induced by HIV infection
Chen et al., Neoplasia (New York, N.Y.) 2009
(Cell Transformation, Neoplastic...) :
By using colony formation in soft agar, ( 3 ) H-TdR incorporation, cell cycle, and microarray gene expression analyses, we demonstrated that
Tat enhanced proliferation as well as
mitogen activated protein kinase , signal transducer and activator of transcription 3, and phosphatidylinositol 3-kinase/protein kinase B signaling induced by Kaposin A in NIH3T3 cells
Fu et al., Journal of neuroinflammation 2011
(HIV Infections...) :
HIV-1
Tat activates indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures in a p38
mitogen activated protein kinase dependent manner
Kim et al., Immune network 2011
:
TAT-CD137Lct increased phosphorylation of Erk, p38
MAPK and Jnk, and activated transcription factors C/EBP and CREB
Gibellini et al., J Immunol 1998
:
Furthermore, extracellular
Tat induced a rapid ( peak at 5-15 min ) stimulation of the
MAPK catalytic activity in primary PBMC