Gene interactions and pathways from curated databases and text-mining

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BMP2 — TCF12

Text-mined interactions from Literome

Dai et al., Dev Biol 2000 : This is the first evidence that Dpp/BMP signaling in flies requires the direct interaction of Mad with a partner transcription factor
Palcy et al., J Bone Miner Res 2000 : Our data emphasize the role of the AP-1 transcription factor in TGF-beta1 and BMP-2 signaling and highlight the importance of this transcription factor family in the expression of OB genes
Feng et al., J Biol Chem 2003 : Here we have used both in vitro and in vivo approaches to demonstrate that transcription factor , NF-kappaB, regulates BMP-2 gene expression in chondrocytes
Diefenderfer et al., J Bone Joint Surg Am 2003 : We hypothesize that the mechanism by which BMPs modulate alkaline phosphatase expression is indirect, involving a BMP regulated transcription factor for alkaline phosphatase expression that is controlled differently in humans and rodents
Phimphilai et al., J Bone Miner Res 2006 : This study shows that autocrine BMP production is necessary for the RUNX2 transcription factor to be active and that BMPs and RUNX2 cooperatively interact to stimulate osteoblast gene expression
Zhao et al., Mol Cell Biol 2006 : The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling
Ikeda et al., J Cell Biochem 2007 : Identification of FAZF as a novel BMP2 induced transcription factor during osteoblastic differentiation
Goldring et al., Ann Rheum Dis 2008 (Osteoarthritis) : These new genes include growth arrest and DNA damage ( GADD ) 45beta and the epithelial-specific ETS (ESE)-1 transcription factor , induced by bone morphogenetic protein (BMP)-2 and inflammatory cytokines, respectively
Fan et al., J Cell Physiol 2009 : Moreover, BMP4 also stimulated expression of transcription factor -- C/EBP-alpha, which involved in differentiation of WB-F344 cells toward hepatocytes
Chae et al., BMB Rep 2009 : Thus, the smpd3 promoter is activated by BMP2 and is directly regulated by the Runx2 transcription factor
Katoh et al., Int J Oncol 2009 : Notch, BMP and Hedgehog signals inhibit WNT2B expression via HES/HEY binding to N-box, whereas BMP and WNT signals inhibit bHLH transcription factor induced WNT2B expression via ID1, ID2, ID3, MSX1 or MSX2
Rajagopal et al., Dev Biol 2009 : Lens formation, placode cell proliferation, the expression of FoxE3, a lens-specific transcription factor , and the lens protein, alphaA-crystallin were regulated by BMP receptors in a Smad independent manner
Mandal et al., Calcif Tissue Int 2010 : Osterix ( Osx ), a BMP-2 regulated transcription factor , controls expression of genes essential for osteoblast differentiation
Dummula et al., J Neurosci 2011 (Cerebral Hemorrhage...) : Importantly, BMP inhibition by recombinant human noggin restored the levels of phospho-Smad1/5/8, Olig2 transcription factor , oligodendrocyte maturation, myelination, astrocyte morphology, and motor function in premature pups with IVH
Viale-Bouroncle et al., Stem Cells Dev 2012 : This transcription factor stimulates the osteogenic differentiation of DFCs and regulates the BMP/SMAD1-pathway
Chen et al., Biochem Biophys Res Commun 2012 : Osterix ( Osx ) is a bone morphogenetic protein 2 (BMP-2) inducible osteoblast-specific transcription factor required for osteoblast differentiation and bone formation