Gene interactions and pathways from curated databases and text-mining

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CASP14 — TRA

Text-mined interactions from Literome

Kendrick et al., Gynecol Oncol 2008 (Uterine Cervical Neoplasms) : IHC revealed an increase in DR5 expression in tumor slices treated with cisplatin for 24 h. IHC and Western blotting demonstrated TRA-8 induced cell death via apoptosis and activation of caspase 3 and 8
Yuan et al., Clin Cancer Res 2013 : PARP-1 knockdown increased TRA-8 induced activation of caspase-8 in the death induced signaling complex ( DISC )