Gene interactions and pathways from curated databases and text-mining

◀ Back to TLR2

TLR2 — TRAF7

Text-mined interactions from Literome

Yoshida et al., J Biol Chem 2005 (Inflammation) : We showed that activation of TLR2 signaling by TLR2 ligands including peptidoglycan ( PGN ), MALP-2, and Pam3CSK4 induces activation of IKKs-IkappaBalpha and MKK3/6-p38 pathways not only by TRAF6 but also by TRAF7 , a recently identified TRAF family member
Clark et al., Proc Natl Acad Sci U S A 2011 : Toll-like receptor ( TLR ) ligands that signal via TIR-domain containing adapter inducing IFNß ( TRIF ) activate the I?B kinase ( IKK ) -related kinases, TRAF associated NF?B activator ( TANK) binding kinase-1 (TBK1 ) and IKKe, which then phosphorylate IRF3 and induce the production of IFNß