Gene interactions and pathways from curated databases and text-mining

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PCNA — VEGFA

Text-mined interactions from Literome

Cheng et al., Life Sci 2005 : The crude extract and fractionated fractions, except for Fra-2, of A. cinnamomea polysaccharides significantly decreased VEGFR2 phosphorylation on tyrosine 1054/1059, cyclin D1 promotor activity, and protein expression induced by VEGF
Mantena et al., J Nutr 2005 (Disease Models, Animal...) : The GTPs+UVB group also had reduced expressions of CD31 and vascular endothelial growth factor , which are essential for angiogenesis, and inhibited expression of proliferating cell nuclear antigen in the tumors compared with the UVB group
Liu et al., Lab Invest 2009 (Disease Models, Animal...) : PTK/ZK also induced cell cycle arrest, accompanied by increasing the expression of p27 ( Kip1 ) and downregulation of cyclin D1 and cyclin E. PTK/ZK significantly inhibited vascular endothelial growth factor ( VEGF ) expression, as well as VEGF simulated cell proliferation and phosphorylation of Akt in activated HSCs
Tsai et al., J Surg Oncol 2013 (Adenocarcinoma...) : Cyclin D1 (CCND1) induces production of VEGF and is required for migration of blood vessels