Gene interactions and pathways from curated databases and text-mining
PTEN: top 25 interacting genes (chr10:89623194-89728532)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only PTEN-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-PTEN interactions     Show top Genes on graph    

Less-frequently mentioned interactions with PTEN, not among the Top 25
Other genes interacting with PTEN. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

AMHR2 ANAPC4 ANAPC5 ANAPC7 ANG ANXA6 AR
ARHGAP26 BAD BAP1 BCL2 BCR BMP1 BMP10
BMP15 BMP2 BMP3 BMP4 BMP5 BMP6 BMP7
BPNT1 CAPN1 CAPN10 CAPN11 CAPN12 CAPN13 CAPN14
CAPN15 CAPN2 CAPN3 CAPN5 CAPN6 CAPN7 CAPN8
CAPN9 CASP1 CASP10 CASP12 CASP14 CASP16 CASP2
CASP3 CASP4 CASP5 CASP6 CASP7 CASP8 CASP9
CCND1 CD79A CD79B CDC27 CDH1 CDIPT CDKN1A
CDKN1B CENPC CFL1 CHGB CHKA COPS6 CREB1
CREB3 CREB5 CRKL CSNK2A1 CSNK2A1P CSNK2A2 CTNNB1
CXCL12 DBF4B DLG1 ECSCR EEF1A2 EGF EGFR
EGR1 EPHB2 FBN2 FBXW7 FOS FOXO1 FOXO3
FRK FUT1 FZR1 G3BP2 GAB1 GABPA GABPB1
GFRA2 GLTSCR2 GPR113 HBA1 HDAC1 HIF1A HRAS
HSPB1 HSPG2 ICAM1 IFI27 IGF1 IGF1R IGF2
IGFBP2 IL18 ILK INHBE INPP4A INPP4B INPP5B
INPP5E IRF6 IRS1 IRS2 IRS4 JUN KAT2B
KRT14 LATS1 LEP LEPREL4 MAGI2 MAP2K1 MAP2K6
MAPK4 MAPK8 MAPK9 MAST1 MAST2 MAST3 MDM2
MED12 MIR21 MLST8 MME MMP2 MMP9 MVP
NDFIP1 NEDD4 NOS3 NOTCH1 OCRL PARK7 PDGFRA
PDPK1 PI4K2A PI4K2B PI4KA PI4KB PIK3C2A PIK3C2B
PIK3C2G PIK3C3 PIK3CB PIK3CD PIK3CG PIK3R2 PIK3R3
PIK3R5 PIKFYVE PIP PIP4K2A PIP4K2B PIP4K2C PIP5K1A
PIP5K1B PIP5K1C PKD1 PKN2 PLCB1 PLCB2 PLCB3
PLCB4 PLCD1 PLCD3 PLCD4 PLCE1 PLCG1 PLCG2
PLCZ1 PPARG PPP1CA PPP2R4 PPP3CA PRDX1 PRDX2
PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PTK2
PTK2B PTPN11 PTPN14 PXN QRFPR RAC1 RAD51
RAPGEF4 ROCK2 RPL14 RPTOR RSL1D1 S1PR2 SERPINB5
SETD2 SHARPIN SKP2 SLC22A3 SLC2A1 SLC2A4 SLC9A3R1
SLC9A3R2 SMAD3 SMTN SP1 SPARC SRC STAT3
STAT5A STUB1 SYNJ1 SYNJ2 SYT1 TCEB3C TCF12
TCF15 TCF19 TCF20 TCF21 TCF23 TCF24 TCF25
TCF3 TCF4 TCF7 TGFB1 TIMP1 TNF TNFSF10
TSC2 TTBK2 TXN TYR UBA52 UBC UBE2I
UBE2L3 UHRF2 USP7 UTP14A VCAM1 WNT4 WWP1
WWP2 ZNF787
Data information
Please see the Gene Interactions Track Manual.