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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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AKT3 — YWHAB

Text-mined interactions from Literome

Guan et al., J Biol Chem 2000 : Furthermore, expression of Akt inhibits epidermal growth factor induced B-Raf activity and inhibition of Akt with LY294002 up-regulates B-Raf activity, suggesting that Akt negatively regulates B-Raf in vivo
Zhang et al., J Biol Chem 2001 : These results indicate that B-Raf kinase activity is negatively regulated by Akt and SGK, suggesting that the cross-talk between the B-Raf and other signaling pathways can be mediated by both Akt and SGK
Shao et al., Cancer Res 2010 (Melanoma) : Importantly, myristylated Akt3 prevented B-RAF targeting induced upregulation of Bim-EL and Bmf in three-dimensional collagen and partially protected Mcl-1 depleted cells from apoptosis
Hong et al., Exp Cell Res 2013 (MAP Kinase Signaling System...) : Using androgen deprived LNCaP cells, in which ERK1/2 activation occurs in strong correlation with AKT activation, we found that AKT mediated B-Raf regulation is necessary for ERK1/2 activation