Gene interactions and pathways from curated databases and text-mining

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AQP5 — PRKAR1B

Text-mined interactions from Literome

Yamamoto et al., Brain Res Mol Brain Res 2002 (Brain Edema) : The dbcAMP induced effects on AQP5 and AQP9 mRNAs were inhibited by PKA inhibitors
Woo et al., Biochem Biophys Res Commun 2008 : These results indicate that, in AQP5, serine156 may be phosphorylated by PKA , but membrane expression of AQP5 may not be regulated by PKA phosphorylation
Kumari et al., Molecular vision 2012 : Effects of phosphokinase A (PKA) agonist cyclic AMP ( cAMP ), and antagonist H-89 on AQP5 expression and localization were studied in vitro using MDCK ( Madin-Darby Canine Kidney ) cells, and ex vivo using isolated corneas from wild type mice ... This is the first report on the spatial expression of AQP5 in the corneal keratocytes and lens epithelial cells, as well as on the regulation of AQP5 localization by PKA in the corneal epithelial cells ... PKA mediated regulation of AQP5 holds promise for therapeutic intervention to control corneal and lens diseases