Gene interactions and pathways from curated databases and text-mining

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CASP7 — CDA

Text-mined interactions from Literome

Chandra et al., Blood 2002 (Calcium Signaling) : In addition, CdA induced caspase-3 activation and DNA fragmentation were inhibited by the Ca2+ chelator BAPTA-AM in sensitive cells
Huang et al., Acta Pharmacol Sin 2008 (Myelodysplastic Syndromes) : Human urine extract CDA-2 induces apoptosis of myelodysplastic syndrome derived MUTZ-1 cells through the PI3K/Akt signaling pathway in a caspase-3 dependent manner
Singh et al., Clin Exp Immunol 2013 (Leukemia, Hairy Cell...) : Furthermore, CdA treatment strongly induced caspase-3 and caspase-9 in monocytes, whereas activation of caspases was undetected in DC
Leoni et al., Proc Natl Acad Sci U S A 1998 : Incubation of the lymphocytes with 2CdA induced caspase-3 activation prior to DNA degradation and cell death