Gene interactions and pathways from curated databases and text-mining

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CASP8 — COL3A1

Pathways - manually collected, often from reviews:

  • NCI Pathway Database Integrins in angiogenesis: Collagen (COL7A1/COL3A1/COL2A1/COL6A1/COL6A2/COL6A3/COL5A1/COL5A2/COL4A4_COL4A3_COL4A6_COL4A1_COL4A5/COL11A1/COL11A2/COL2A1/COL1A1/COL1A2) → Caspase 8 (CASP8) (modification, activates) Stupack et al., J Cell Biol 2001
    Evidence: mutant phenotype, assay, physical interaction