Gene interactions and pathways from curated databases and text-mining

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CREB5 — PCNA

Text-mined interactions from Literome

Kibler et al., J Virol 2001 (HTLV-I Infections) : CREB/ATF dependent repression of cyclin a by human T-cell leukemia virus type 1 Tax protein
Shin et al., Med Electron Microsc 2002 : Because the PCNA gene has a cAMP-responsive element in its promoter, it can be suggested that CREB may activate the PCNA gene and lead to the induction of hepatocyte DNA synthesis
Amorino et al., J Biol Chem 2003 (MAP Kinase Signaling System) : Dominant negative cAMP-responsive element binding protein inhibits proliferating cell nuclear antigen and DNA repair, leading to increased cellular radiosensitivity
Sharma et al., Biochem Biophys Res Commun 2007 (MAP Kinase Signaling System) : Cyclin dependent kinase 5 (Cdk5) mediated inhibition of the MAP kinase pathway results in CREB down regulation and apoptosis in PC12 cells
Belkowski et al., J Immunol 1998 : However, phosphorylation of CREB alone is not sufficient to drive PCNA expression and L2 cell proliferation in the absence of IL-2