Gene interactions and pathways from curated databases and text-mining

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BMP2 — FGF14

Text-mined interactions from Literome

Choi et al., Dev Dyn 2005 : These results indicate that Runx2 is an important mediator of the expression of Bmp2 in response to FGF stimulation in cranial bone development
Fakhry et al., Bone 2005 : Furthermore, FGF-2 and FGF-9 increased expression of other osteogenic factors BMP-2 and TGFbeta-1
Sandell et al., Osteoarthritis Cartilage 2008 (Arthritis) : In the presence of IL-1beta, FGF-18 increased expression of ADAMTS-4, aggrecan, BMP-2 , COL2A1, CCL3, CCL4, CCL20, CXCL1, CXCL3, CXCL6, IL-1beta, IL-6, and IL-8 and decreased ADAMTS-5, MMP-13, CCL2, and CCL8
Xu et al., Cell stem cell 2008 : Using a defined medium, we show here that both TGFbeta and FGF signals synergize to inhibit BMP signaling ; sustain expression of pluripotency associated genes such as NANOG, OCT4, and SOX2 ; and promote long-term undifferentiated proliferation of human ESCs
Boswell et al., Dev Biol 2008 : Although BMP signaling is required for FGF to enhance fiber differentiation, the converse is not true
Lee et al., Biochim Biophys Acta 2009 : This process requires, at least in part, the inhibition of BMP signalling in the ectoderm by noggin, as well as FGF receptor activation and Ca2+ signalling
Maatouk et al., Dev Biol 2009 (Limb Deformities, Congenital) : At the molecular level, removal of Bmp2 and Bmp4 in the AER caused an increase in Fgf expression, which correlated with an increase in both the width and length of the AER
Huang et al., Development 2009 : FGF regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate
Mackem et al., Science signaling 2009 : In turn, SHH activity maintains the expression of Gremlin1, which encodes a bone morphogenetic protein ( BMP ) antagonist ; the interaction between BMP and Gremlin1 regulates Fgf gene expression
Tirosh-Finkel et al., Development 2010 : BMP mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors
Yardley et al., Dev Biol 2012 : Finally, we report that prior to the upregulation of these neural crest markers, the non-neural ectoderm upregulates both BMP and Wnt molecules in response to FGF
Lupo et al., Open biology 2013 : We show that either BMP inhibition or activation of FGF signalling is required for effective neural induction, but these two pathways have distinct outcomes on rostrocaudal patterning
Sabbieti et al., Endocrinology 2013 : Basal expression of FGF receptor 1 protein was significantly increased in Tg ( LMW ) COBs relative to Tg ( Vector ) COBs, and although BMP-2 caused a transient increase in FGF receptor 1 expression in Tg ( Vector ) COBs and Tg ( HMW ) COBs, there was no further increase Tg ( LMW ) COBs