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FGFR3 — PLD4
Text-mined interactions from Literome
Mamoon et al., J Pharmacol Exp Ther 1999
:
Inhibition of protein kinase C with calphostin C or bisindolylmaleimide I had no effect on isoproterenol- or forskolin stimulated PLD activity but inhibited
ACh activated
PLD activity ... PKA inhibition also eliminated inhibition of
ACh stimulated
PLD activity by forskolin or isoproterenol ... These results suggest that increasing the concentration of cAMP activates PLD via activation of PKA and that the increased activity of PKA also
inhibits cholinergic stimulation of
PLD , in part at least by inhibiting the activation of phospholipase C by
ACh
Mamoon et al., J Biomed Sci 2004
:
Activation of
ACh induced
PLD was inhibited by the tyrosine kinase inhibitor genistein in a concentration dependent manner