Gene interactions and pathways from curated databases and text-mining

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EGFR — GNRH2

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: EGFR → GNRH2 (decreases, GNRH2 Activity) Günthert et al., Eur J Endocrinol 2005*
    Evidence: Pretreatment with Triptorelin or [d-Lys(6)]GnRH-II blocked EGF-induced autophosphoryla-tion of EGF receptor and activation of mitogen-activated protein kinase (extracellular-signal-regulated kinase 1/2 (ERK1/2)) in these cells.