Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Jin et al., Neuropharmacology 2005 : Opposite effects of lithium and valproic acid on trophic factor deprivation induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death
Hu et al., J Leukoc Biol 2007 : IFN-gamma synergizes with TLRs in part by suppressing TLR induced feedback inhibition, mediated by IL-10 and Stat3, by a mechanism that depends on glycogen synthase kinase ( GSK ) 3 regulation of AP-1 and CREB
Liu et al., Neurobiol Aging 2009 : Inhibition of proteasome resulted in activation of cAMP dependent protein kinase, glycogen synthase kinases-3beta and cyclin dependent kinase-5, and inhibition of protein phosphatase-2A and c-Jun N-terminal kinase (JNK)
Singh et al., Nat Methods 2012 : We analyzed the c-Jun N-terminal kinase (JNK) dependent glycogen synthase kinase 3ß ( GSK3ß ) activity on doublecortin ( DCX ) revealing mechanistic details about the role of phosphorylation cross-talk in GSK3ß activity and permitting an advanced model for GSK3ß mediated signaling