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GZMB — IL12A
Text-mined interactions from Literome
Marshall et al., J Immunol 2010
(Arenaviridae Infections) :
IL-12 , IL-15, IL-18, and IFN-gamma were not individually required for sensitization to produce IFN-gamma, but IL-15 was
required for upregulation of
granzyme B
Hwang et al., PloS one 2012
(Influenza, Human) :
Analysis of cytokine receptor deficient mice demonstrated that type I interferons ( IFNs ), but not
IL-12 or IL-18, were
critical for the NK cell expression of both IFN-? and
granzyme B in response to flu infection
Chouaib et al., Proc Natl Acad Sci U S A 1994
:
IL-12 increased
granzyme B and perforin mRNA accumulation in major histocompatibility complex class I-primed lymphocytes, suggesting that this cytokine activates these two genes in CTL precursors
Aste-Amezaga et al., Cell Immunol 1994
:
IL-12 induction of perforin mRNA accumulation was not synergistic with either IL-2 or anti-CD16 stimulation, whereas
granzyme B mRNA accumulation, induced by IL-2 or anti-CD16 stimulation, was slightly
potentiated by
IL-12