Gene interactions and pathways from curated databases and text-mining

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CASP12 — HIP1

Text-mined interactions from Literome

Gervais et al., Nat Cell Biol 2002 (Huntington Disease) : Recruitment and activation of caspase-8 by the Huntingtin interacting protein Hip-1 and a novel partner Hippi
Wanker et al., Dev Cell 2002 (Huntington Disease) : Biochemical and cell biological studies point to a role for Hip1 and Hippi in caspase-8 activation and the initiation of apoptosis during the pathogenesis of Huntington 's disease
Banerjee et al., Nucleic Acids Res 2010 : Taking together, we are able to show the importance of R393 of HIPPI and the role of HIPPI-HIP-1 heterodimer in the transcription regulation of caspase-1