Gene interactions and pathways from curated databases and text-mining

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IDDM18 — IL2

Text-mined interactions from Literome

Sjöholm et al., Cell Death Differ 1998 (Diabetes Mellitus, Type 1) : Aspects of the involvement of interleukin-1 and nitric oxide in the pathogenesis of insulin dependent diabetes mellitus
Fraenkel et al., J Immunother 2002 (Carcinoma, Renal Cell...) : Induction of myasthenia gravis, myositis, and insulin dependent diabetes mellitus by high-dose interleukin-2 in a patient with renal cell cancer
von Herrath et al., J Clin Invest 1995 (Autoimmune Diseases...) : The participation of IL-2 in insulin dependent ( type 1 ) diabetes ( IDDM ) was analyzed in transgenic ( tg ) mice expressing the nucleoprotein ( NP ) of lymphocytic choriomeningitis virus and IL-2 under control of the rat insulin promoter focally in beta cells of the islets of Langerhans ... Insertion and expression of the viral ( self ) gene or of the IL-2 gene alone did not lead to IDDM