◀ Back to CDKN1A
CDKN1A — IFI27
Text-mined interactions from Literome
Chang et al., Cancer Lett 1999
(Lung Neoplasms) :
Moreover, mimosine
induced p21CIP1 expression in H226 and H358 cells, while it activated
p27KIP1 expression in H322 cells
Sasaki et al., Brain Res Mol Brain Res 2000
:
In a mutant P19 cell line, RAC65, treatment with ATRA induced neither
p27 accumulation nor neuronal differentiation, but
p21 mRNA expression
increased markedly
Wartenberg et al., Biochim Biophys Acta 2002
(Prostatic Neoplasms) :
Staurosporine
induced upregulation of
p21 ( WAF-1 ) whereas
p27 ( Kip1 ) remained unaltered
Pozo-Guisado et al., Biochem Pharmacol 2002
(Breast Neoplasms) :
Simultaneously,
p21 expression was markedly induced in
presence of high levels of
p27 and p53
Jackson et al., Oncogene 2002
(Cell Transformation, Neoplastic...) :
Collectively, our data suggest that
p21 ( Cip1 ) suppresses tumor formation elicited by multiple agents and that p21 ( Cip1 ) and
p27 ( Kip1 )
suppress tumor formation in different ways
Kim et al., Angiogenesis 2005
:
In Western blot analysis, bFGF induced cytoplasmic translocation of p21 ( Waf1/Cip1 ) and
p27 ( Kip1 ) and phosphorylation of p27 ( Kip1 ) but rk-2 treatment
inhibited translocation of
p21 ( Waf1/Cip1 ) and p27 ( Kip1 ) from nucleus to cytoplasm and phosphorylation of p27 ( Kip1 )
He et al., Br J Cancer 2006
:
Moreover, DAP induced
p21 promoted the selective increase of
p27 in the CDK2 complex, but not in CDK4 complex, and this selective increase contributed to inhibition of the CDK2 kinase activity