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BCL3 — IL10

Text-mined interactions from Literome

Kuwata et al., Blood 2003 : These findings suggest that IL-10 induced Bcl-3 is required for suppression of TNF-alpha production in macrophages
Kalechman et al., J Biol Chem 2004 (Glomerulonephritis) : IL-10 increased MC expression of Bcl-2 and Bcl-X1 and simultaneously decreased the levels of p27kip1
Riemann et al., J Immunol 2005 (Listeriosis) : The IkappaB protein Bcl-3 negatively regulates transcription of the IL-10 gene in macrophages
Brocke-Heidrich et al., Oncogene 2006 (Multiple Myeloma) : In this study, interleukin (IL)-6 induced BCL3 expression and its effect on survival of multiple myeloma ( MM ) cells were examined
Jarry et al., J Clin Invest 2008 : Depletion of IL-10 in mucosal explants induced both downregulation of the IL-10-inducible, immunosuppressive gene BCL3 and upregulation of IFN-gamma, TNF-alpha, and IL-17
Dagvadorj et al., Innate Immun 2009 : Therefore, it was suggested that Bcl-3 induced by IL-10 might reduce LPS induced IkappaB-zeta activity via inactivation of NF-kappaB and that reduced IkappaB-zeta activity failed to promote LPS induced IL-6 production