Gene interactions and pathways from curated databases and text-mining

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IL17D — IRF1

Text-mined interactions from Literome

Remoli et al., Eur J Immunol 2007 : IFN-beta modulates the response to TLR stimulation in human DC : involvement of IFN regulatory factor-1 (IRF-1) in IL-27 gene expression
Yoshimoto et al., J Immunol 2008 (Melanoma, Experimental) : IL-27 augmented the expression of IFN regulatory factor (IRF)-1 and IRF-8, which possess tumor suppressor activities, in B16F10 transfectants expressing wild-type WSX-1
Molle et al., J Immunol 2010 : Involvement of IRF1 and IRF9 in the induction of IL-27p28 was confirmed in vitro and upon in vivo exposure to TLR ligands
Zhang et al., J Biol Chem 2010 (Inflammation) : Our previous work has shown that IRF-1 regulates IL-27 p28 gene transcription by specifically binding to the IRF-1 response element in the p28 promoter ... Consistent with this observation, overexpression of both IRF-8 and IRF-1 additively activated IL-27 p28 promoter