◀ Back to GSK3B
GSK3B — IL1B
Text-mined interactions from Literome
Vines et al., J Biol Chem 2006
:
We observed that tumor necrosis factor-alpha (TNF-alpha) and
interleukin-1beta (IL-1beta) treatment of primary cultures of human microvascular cells
reduced net endogenous active
GSK-3beta protein levels while inducing inflammatory cytokine ( IL-6 and monocyte chemoattractant protein-1 ( MCP-1 ) ) expression
Kaler et al., Oncogene 2009
:
Tumor cells induced the release of interleukin
(IL)-1beta from macrophages, which
induced phosphorylation of
GSK3beta , stabilized beta-catenin, enhanced T-cell factor ( TCF ) -dependent gene activation and induced the expression of Wnt target genes in tumor cells