◀ Back to STAT3

IL7 — STAT3

Text-mined interactions from Literome

Demoulin et al., Cytokines Cell Mol Ther 1998 : IL-2, IL-7 , IL-9 and IL-15 activate STAT3 and STAT5, in contrast to IL-4, which activates STAT6
O'Brien et al., J Biol Chem 1999 : STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130 utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroid hormone
Sawa et al., J Exp Med 2006 (Arthritis...) : Conditional knockout of STAT3 in nonlymphoid cells showed that the enhancement of IL-7 production was dependent on STAT3 activation by IL-6 family cytokines ... Thus, our results show that autoimmune disease in gp130 mutant mice is caused by increased homeostatic proliferation of CD4+ T cells, which is due to elevated production of IL-7 by nonhematopoietic cells as a result of IL-6 family cytokine-gp130-STAT3 signaling
Ozawa et al., Journal of ophthalmology 2011 : In innate chorioretinal inflammation, interleukin-6 family ligands induce STAT3 activation in photoreceptors, which causes UPS mediated excessive degradation of the visual substance, rhodopsin
van der Plas et al., Leukemia 1996 (Burkitt Lymphoma...) : These findings establish that STAT1 and STAT5, and possibly STAT3 , are activated upon stimulation of precursor B cells with IL-7