Németh et al., Am J Pathol 2002
(MAP Kinase Signaling System) :
Hyperosmolarity activated both p38 and p42/44 mitogen activated protein kinases, which effect contributed to hyperosmolarity stimulated IL-8 production, because p38 and p42/44 inhibition prevented the hyperosmolarity induced increase in IL-8 production
Shen et al., Immunology 2006
:
However, IL-8 mediated phosphorylation of p44/42 mitogen activated protein kinase was greatly reduced in neutrophils that no longer migrated to IL-8, and was diminished in cells that no longer migrated to fMLP
Ostrowska et al., Biochem Biophys Res Commun 2008
:
Protease activated receptor (PAR) induced interleukin-8 production in airway epithelial cells requires activation of MAP kinases p44/42 and JNK