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IRF6 — NOTCH3

Text-mined interactions from Literome

Xing et al., J Cell Physiol 2010 : P-LPS stimulation activated the Notch1 signaling cascade and increased expression of the Notch target genes HES1 and HEY1
Outtz et al., J Immunol 2010 (Inflammation) : Inhibition of Notch signaling decreased induction of the inflammatory cytokines IL-6, IL-12, CXCL10, MCP-1, monokine induced by IFN-?, and TNF-a in macrophages in response to LPS/IFN-?
Zhang et al., J Biol Chem 2012 (Inflammation...) : The expression of Notch target genes including Hes1 and Hes5 was also induced in macrophages by LPS , suggesting that TLR4 signaling enhances the activation of Notch pathway
Larabee et al., J Biol Chem 2013 : Overexpression studies indicated that RBP-J was sufficient to activate Notch signaling and potentiate LPS induced Notch signaling