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CD4 — IRF7

Text-mined interactions from Literome

Fanning et al., J Immunol 2006 : Taken together, these results suggest that cross linking BDCA-2, BDCA-4, and CD4 on PDC regulates IFN-alpha production at the level of IRF-7 , while the decrease in IFN-alpha production after CD123 cross linking is due to stimulation of the IL-3R and induction of PDC maturation
Biswas et al., J Exp Med 2012 (Autoimmune Diseases...) : In CD4 ( + ) T helper cells, IRF4 plays an essential role in the regulation of IL-21 production, whereas in B cells it controls class switch recombination and plasma cell differentiation