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ITGB1 — MAPK14

Text-mined interactions from Literome

Qiang et al., Exp Hematol 2000 : Activation of mitogen activated protein kinase through alpha5/beta1 integrin is required for cell cycle progression of B progenitor cell line, Reh, on human marrow stromal cells
Bhowmick et al., J Biol Chem 2001 : Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity ... In summary, TGF-beta mediated p38MAPK activation is dependent on functional integrin beta(1) , and p38MAPK activity is required but is not sufficient to induce EMT
Sato et al., Cancer Res 2005 (Lymphoma, Large B-Cell, Diffuse...) : CD26 regulates p38 mitogen activated protein kinase dependent phosphorylation of integrin beta1 , adhesion to extracellular matrix, and tumorigenicity of T-anaplastic large cell lymphoma Karpas 299 ... Moreover, our data showing that the p38MAPK inhibitor SB203580 dephosphorylates integrin beta1 and that binding of the anti-CD26 antibody 202.36 dephosphorylates both p38MAPK and integrin beta1 on Karpas 299, leading to loss of cell adhesion to the extracellular matrix, indicate that CD26 mediates cell adhesion through p38MAPK dependent phosphorylation of integrin beta1
Camacho-Leal et al., J Cell Physiol 2007 (MAP Kinase Signaling System) : Inhibition of PI3-K and ILK, but not MAPK , prevented the alpha5beta1 integrin activation
Reyes-Reyes et al., Exp Cell Res 2008 (Adenocarcinoma...) : We have previously shown that P-selectin binding to Colo-320 human colon carcinoma cells induces specific activation of the alpha(5)beta(1) integrin with a concomitant increase of cell adhesion and spreading on fibronectin substrates in a phosphatidylinositol 3-kinase (PI3-K) and p38 MAPK dependent manner