Gene interactions and pathways from curated databases and text-mining

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MAPK3 — NEUROD1

Text-mined interactions from Literome

Yamashita et al., J Biol Chem 2000 : Thus, co-activation of Rap1 by CalDAG-GEFIII apparently attenuated Ras-MAPK dependent neuronal differentiation and cellular transformation
Hansen et al., J Neurochem 2000 : The results indicate that p38 MAPK is a downstream target of the cAMP signaling pathway and that p38 MAPK plays a key role in neuronal differentiation induced by cAMP and growth factors by integration of signals from both pathways
Taraviras et al., Eur J Cell Biol 2002 (MAP Kinase Signaling System) : Epinephrine induced neuronal differentiation of PC12alpha2 cells through alpha2-AR activation in a subtype dependent manner, internalization of all human alpha2-AR subtypes, and activation of mitogen activated protein kinase ( MAPK ) and the serine-threonine protein kinase Akt
Kutcher et al., Am J Physiol Cell Physiol 2003 (MAP Kinase Signaling System) : Inhibition of neuronal differentiation by nuclear CaMKII was independent of MAPK signaling, as sustained Erk phosphorylation was not affected
Hetman et al., Eur J Biochem 2004 (MAP Kinase Signaling System) : In the nervous system, ERK1/2 is critical for neuronal differentiation , plasticity and may also modulate neuronal survival
Li et al., Dev Growth Differ 2006 (MAP Kinase Signaling System) : Role of ERK 1/2 signaling in neuronal differentiation of cultured embryonic stem cells
Yang et al., J Biol Chem 2008 (MAP Kinase Signaling System) : Basic fibroblast growth factor induced neuronal differentiation of mouse bone marrow stromal cells requires FGFR-1, MAPK/ERK , and transcription factor AP-1 ... Moreover, we have shown that the mitogen activated protein kinase ( ERK1/2 ) is persistently activated and blockage of ERK activity with the ERK-specific inhibitor U0126 prevents neuronal differentiation
Wang et al., Neurosci Lett 2009 : Erk1/2 promotes proliferation and inhibits neuronal differentiation of neural stem cells
Li et al., Chembiochem 2011 : Taken together, our findings suggest that baicalin induces neuronal differentiation of C17.2 neural stem cells and that this is mediated by activation of Erk1/2
Kim et al., J Biol Chem 1997 : We further examined the role of mitogen activated protein kinase activation in IGF-I stimulated neuronal differentiation using the mitogen activated protein kinase/ERK kinase inhibitor PD98059
Yao et al., J Biol Chem 1998 : Induction of neuronal differentiation of the rat pheochromocytoma cell line, PC12 cells, by nerve growth factor (NGF) requires activation of the mitogen activated protein ( MAP ) kinase or extracellular signal regulated kinase ( ERK )